D
Cassiopeia Build / Runes
the Serpent's Embrace • Platinum+
Best Cassiopeia Build on Mid for patch 14.22. Find the Cassiopeia Runes you are looking for!
1.5%
Pick Rate
52.4%
Win Rate
1.3%
Ban Rate
19,132
Matches
Strong against
38.2%
220
42.2%
244
42.8%
362
43.1%
269
44.7%
904
Weak against
55%
469
53.2%
267
51.9%
424
51.7%
603
50.7%
1,313
Summoner Spells
52.5%
16,500 Matches
Starter Items
2
52.7%
13,609 Matches
Core Items
58.6%
5,195 Matches
Late Game Items
58.7%63.5%61.7%
Spell Skill Priority
E
Q
W
54%
10,543 Matches
Q
2
8
10
12
13
W
3
14
15
E
1
4
5
7
9
R
6
11
Cassiopeia Runes
Precision
Sorcery
lolvvv Cassiopeia Runes
Cassiopeia RunesPrecision0%
0%
0%
100%
0%
0%
100%
<1%
>99%
0%
<1%
78%
22%
Sorcery0%
>99%
<1%
66%
20%
0%
14%
0%
<1%
48%
26%
26%
91%
8%
<1%
50%
8%
42%
Lore
Ally Tips
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
Lead your enemy when targeting with Noxious Blast to ensure the hit.
Enemy Tips
Be wary of Cassiopeia Runes's damage potential with Twin Fang when she has you poisoned.
Turn away from Cassiopeia Runes when she is casting Petrifying Gaze to get slowed instead of stunned.
Cassiopeia Runes is a deadly creature bent on manipulating others to her sinister will. Youngest and most beautiful daughter of the noble Du Couteau family of Noxus, she ventured deep into the crypts beneath Shurima in search of ancient power. There, she was bitten by a gruesome tomb guardian, whose venom transformed her into a viper-like predator. Cunning and agile, Cassiopeia Runes now slithers under the veil of night, petrifying her enemies with her baleful gaze.