Cassiopeia
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Cassiopeia Build / Runes

the Serpent's Embrace • Platinum+
TOPJUNGLEMIDDLEADCARRYSUPPORT
Best Cassiopeia Build on Support for patch 14.22. Find the Cassiopeia Runes you are looking for!
0%
Pick Rate
43.5%
Win Rate
1.3%
Ban Rate
354
Matches

Strong against

Hwei
20%
5
Vel'Koz
20%
5
Bard
20%
5
Neeko
25%
8
Shen
25%
4

Weak against

Braum
100%
4
Brand
100%
7
Lulu
88.9%
9
Pyke
87.5%
8
Teemo
80%
5

Summoner Spells

ExhaustFlash
51.5%
68 Matches

Starter Items

Health Potion
2
World Atlas
45.4%
284 Matches

Core Items

Zaz'Zak's RealmspikeArchangel's StaffLiandry's Torment
72.7%
11 Matches

Late Game Items

Rylai's Crystal Scepter
Blackfire Torch
Zhonya's Hourglass
52.6%76.9%60%

Spell Skill Priority

Twin Fang
E
Noxious Blast
Q
Miasma
W
90%
10 Matches
Noxious Blast
Q
3
8
10
12
13
Miasma
W
2
14
15
Twin Fang
E
1
4
5
7
9
Petrifying Gaze
R
6
11

Cassiopeia Runes

PrecisionPrecision
Press the Attack
Lethal Tempo
Fleet Footwork
Conqueror
Absorb Life
Triumph
Presence of Mind
Legend: Alacrity
Legend: Haste
Legend: Bloodline
Coup de Grace
Cut Down
Last Stand
SorcerySorcery
Nullifying Orb
Manaflow Band
Nimbus Cloak
Transcendence
Celerity
Absolute Focus
Scorch
Waterwalking
Gathering Storm
Adapative Force
Attack Speed
Ability Haste
Adapative Force
Move Speed
Health Scaling
Base Health
Tenacity and Slow Resist
Health Scaling

lolvvv Cassiopeia Runes

Cassiopeia Runes

Lore

Ally Tips

Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.

Lead your enemy when targeting with Noxious Blast to ensure the hit.

Enemy Tips

Be wary of Cassiopeia Runes's damage potential with Twin Fang when she has you poisoned.

Turn away from Cassiopeia Runes when she is casting Petrifying Gaze to get slowed instead of stunned.

Cassiopeia Runes is a deadly creature bent on manipulating others to her sinister will. Youngest and most beautiful daughter of the noble Du Couteau family of Noxus, she ventured deep into the crypts beneath Shurima in search of ancient power. There, she was bitten by a gruesome tomb guardian, whose venom transformed her into a viper-like predator. Cunning and agile, Cassiopeia Runes now slithers under the veil of night, petrifying her enemies with her baleful gaze.