Cassiopeia
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Cassiopeia Build / Runes

the Serpent's Embrace • Platinum+
TOPJUNGLEMIDDLEADCARRYSUPPORT
Best Cassiopeia Build on Support for patch 15.1. Find the Cassiopeia Runes you are looking for!
0%
Pick Rate
45.8%
Win Rate
4.6%
Ban Rate
1,474
Matches

Strong against

Rakan
30.4%
23
Malphite
36.8%
19
Alistar
40%
15
Soraka
40%
20
Thresh
40.6%
64

Weak against

Bard
87.5%
16
Yuumi
70.4%
27
Senna
69.7%
33
Milio
68%
25
Maokai
67.6%
34

Summoner Spells

FlashHeal
50.7%
213 Matches

Starter Items

Health Potion
2
World Atlas
46.3%
1,187 Matches

Core Items

Zaz'Zak's RealmspikeRod of AgesRylai's Crystal Scepter
63.4%
41 Matches

Late Game Items

Archangel's Staff
Liandry's Torment
Morellonomicon
51.6%61.1%63.6%

Spell Skill Priority

Twin Fang
E
Noxious Blast
Q
Miasma
W
53%
202 Matches
Noxious Blast
Q
1
8
10
12
13
Miasma
W
3
14
15
Twin Fang
E
2
4
5
7
9
Petrifying Gaze
R
6
11

Cassiopeia Runes

PrecisionPrecision
Press the Attack
Lethal Tempo
Fleet Footwork
Conqueror
Absorb Life
Triumph
Presence of Mind
Legend: Alacrity
Legend: Haste
Legend: Bloodline
Coup de Grace
Cut Down
Last Stand
SorcerySorcery
Axiom Arcanist
Manaflow Band
Nimbus Cloak
Transcendence
Celerity
Absolute Focus
Scorch
Waterwalking
Gathering Storm
Adapative Force
Attack Speed
Ability Haste
Adapative Force
Move Speed
Health Scaling
Base Health
Tenacity and Slow Resist
Health Scaling

lolvvv Cassiopeia Runes

Cassiopeia Runes

Lore

Ally Tips

Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.

Lead your enemy when targeting with Noxious Blast to ensure the hit.

Enemy Tips

Be wary of Cassiopeia Runes's damage potential with Twin Fang when she has you poisoned.

Turn away from Cassiopeia Runes when she is casting Petrifying Gaze to get slowed instead of stunned.

Cassiopeia Runes is a deadly creature bent on manipulating others to her sinister will. Youngest and most beautiful daughter of the noble Du Couteau family of Noxus, she ventured deep into the crypts beneath Shurima in search of ancient power. There, she was bitten by a gruesome tomb guardian, whose venom transformed her into a viper-like predator. Cunning and agile, Cassiopeia Runes now slithers under the veil of night, petrifying her enemies with her baleful gaze.